Pipernonaline

SKU HY-W748509-Get quote Category Tags , ,
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Product Description

– Pipernonaline is a piperine derivative with antiprostate cancer activity. Pipernonaline inhibits the proliferation of androgen-dependent/independent LNCaP/PC-3 prostate cells. Pipernonaline activates caspase-3 and promotes procaspase-3/PARP cleavage. Pipernonaline also mediates reactive oxygen species (ROS) production, increased intracellular Ca(2+), and mitochondrial membrane depolarization[1].

Web ID

– HY-W748509

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C21H27NO3

References

– [1]Lee W, et al. Pipernonaline from Piper longum Linn. induces ROS-mediated apoptosis in human prostate cancer PC-3 cells. Biochem Biophys Res Commun. 2013 Jan 4;430(1):406-12..

CAS Number

– 88660-10-0

Molecular Weight

– 341.44

SMILES

– O=C(N1CCCCC1)/C=C/CCCC/C=C/C2=CC=C(OCO3)C3=C2

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Apoptosis, Caspase

Pathway

– Apoptosis

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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