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Piperlongumine
Price range: 48 CAD through 195 CAD
Products Details
Product Description
– Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
Web ID
– T6947
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H19NO5
Citations
– 1. Qiu C, Shen X, Lu H, et al.Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells.Cell Death Discovery.2023, 9(1): 375.
2. Kong Y, Liu Y, Li X, et al.Palmitoylation landscapes across human cancers reveal a role of palmitoylation in tumorigenesis.Journal of Translational Medicine.2023, 21(1): 1-19.
3. Ibrahim F A R, Hussein N A, Soliman A Y M, et al.Chitosan-loaded piperlongumine nanoparticles and kaempferol enhance the anti-cancer action of doxorubicin in targeting of Ehrlich solid adenocarcinoma: in vivo and in silico modeling study.Medical Oncology.2024, 41(2): 1-17.
References
– Yao Y, et al. Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells. Oncotarget. 2016 Nov 8;7(45):73497-73508.
CAS Number
– 20069-09-4
Molecular Weight
– C17H19NO5
Compound Purity
– 0.9989
SMILES
– COc1cc(C=CC(=O)N2CCC=CC2=O)cc(OC)c1OC
Pathway
– Microbiology/Virology|||MAPK|||Autophagy|||Immunology/Inflammation|||Metabolism|||Apoptosis|||NF-κB
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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