Download Files:
Pipecuronium (bromide)
$100 – $820
Products Details
Product Description
– Pipecuronium bromide is a potent long-acting nondepolarizing steroidal neuromuscular blocking agent (NMBA), and a bisquaternary ammonium compound. Pipecuronium bromide is a powerful competitive nAChR antagonist with a Kd of 3.06 μM[1][2][3][4][5].
Web ID
– HY-B0743A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C35H62Br2N4O4
References
– [1]Tassonyi E, et al. Reversal of Pipecuronium-Induced Moderate Neuromuscular Block with Sugammadex in the Presence of a Sevoflurane Anesthetic: A Randomized Trial. Anesth Analg. 2015 Aug;121(2):373-80.|[2]Tassonyi E, et al. Reversal of Deep Pipecuronium-Induced Neuromuscular Block With Moderate Versus Standard Dose of Sugammadex: A Randomized, Double-Blind, Noninferiority Trial. Anesth Analg. 2018 Dec;127(6):1344-1350.|[3]Alánt O, et al. First clinical experience with a new neuromuscular blocker pipecurium bromide. Arzneimittelforschung. 1980;30(2a):374-9.|[4]Töröcsik A, et al. Characterization of somatodendritic neuronal nicotinic receptors located on the myenteric plexus. Eur J Pharmacol. 1991 Sep 24;202(3):297-302.|[5]Kárpáti E, et al. Investigation of neuromuscular blocking agents at Richter Ltd. Acta Pharm Hung. 2002;72(1):37-48.
CAS Number
– 52212-02-9
Molecular Weight
– 762.70
Compound Purity
– 98.71
SMILES
– C[C@@]1([C@H]2OC(C)=O)[C@](C[C@@H]2N3CC[N+](C)(C)CC3)([H])[C@@](CC[C@]4([H])[C@@]5(C[C@H](N6CC[N+](C)(C)CC6)[C@@H](OC(C)=O)C4)C)([H])[C@]5([H])CC1.[Br-].[Br-]
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– DMSO : 150 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
