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Pim-1 kinase inhibitor 6
Products Details
Product Description
– Pim-1 kinase inhibitor 6 (Compound 4d) is a potent Pim-1 kinase inhibitor with IC50 value of 0.46 μM, and has significant cytotoxic effect on cancer cells[1].
Web ID
– HY-149996
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H10BrCl2N3
References
– [1]Basem Mansour, et al. Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim-1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation. ACS Omega. 2023 May 24;8(22):19351-19366.
CAS Number
– 2928606-69-1
Molecular Weight
– 455.13
SMILES
– ClC(C(C1=CC(C2=CC=C(Br)C=C2)=NC(Cl)=C1C#N)=C3)=NC4=C3C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Pim
Pathway
– JAK/STAT Signaling
Product type
– Reference compound
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