Pim-1 kinase inhibitor 6

SKU HY-149996-Get quote Category Tags , ,

Products Details

Product Description

– Pim-1 kinase inhibitor 6 (Compound 4d) is a potent Pim-1 kinase inhibitor with IC50 value of 0.46 μM, and has significant cytotoxic effect on cancer cells[1].

Web ID

– HY-149996

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C21H10BrCl2N3

References

– [1]Basem Mansour, et al. Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim-1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation. ACS Omega. 2023 May 24;8(22):19351-19366.

CAS Number

– 2928606-69-1

Molecular Weight

– 455.13

SMILES

– ClC(C(C1=CC(C2=CC=C(Br)C=C2)=NC(Cl)=C1C#N)=C3)=NC4=C3C=CC=C4

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Pim

Pathway

– JAK/STAT Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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