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Products Details
Product Description
– phoBET1 is a photocaged-PROTAC. phoBET1 can achieve BRD4 degradation and effectively suppress tumor growth[1].
Web ID
– HY-149328
Shipping
– Room temperature
Molecular Formula
– C52H56ClN11O13S
References
– [1]He Q, et al. Near-Infrared-Activatable PROTAC Nanocages for Controllable Target Protein Degradation and On-Demand Antitumor Therapy. J Med Chem. 2023 Jun 6.
Molecular Weight
– 1110.58
SMILES
– COC1=CC(C(OCN(C(CCC2N3C(C4=CC=CC(OCC(NCCCCNC(C[C@H]5C6=NN=C(N6C7=C(C(C8=CC=C(C=C8)Cl)=N5)C(C)=C(C)S7)C)=O)=O)=C4C3=O)=O)=O)C2=O)C)=C(C=C1OCC(NCCN)=O)[N+]([O-])=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PROTACs
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
