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Phenylbiguanide
$50 – $55
Products Details
Product Description
– Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
Web ID
– HY-101331
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C8H11N5
References
– [1]Mair ID, et al. Pharmacological characterization of a rat 5-hydroxytryptamine type3 receptor subunit (r5-HT<sub>3A(b)</sub>) expressed in <i>Xenopus laevis</i> oocytes. Br J Pharmacol. 1998 Aug;124(8):1667-74.|[2]Ataee R, et al. Study of 5HT3 and HT4 receptor expression in HT29 cell line and human colon adenocarcinoma tissues. Arch Iran Med. 2010 Mar;13(2):120-5.|[3]de Vries A, et al. Characterisation of c-Fos expression in the central nervous system of mice following right atrialinjections of the 5-HT3 receptor agonist Phenylbiguanide. Auton Neurosci. 2005 Dec 30;123(1-2):62-75.
CAS Number
– 102-02-3
Molecular Weight
– 177.21
Compound Purity
– 98.0
SMILES
– NC(NC(NC1=CC=CC=C1)=N)=N
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 150 mg/mL (ultrasonic)|H2O : ≥ 25 mg/mL
Target
– 5-HT Receptor
Isoform
– 5-HT3 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
