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Phentolamine
$50
Only 1000 item(s) left in stock.
Products Details
Product Description
– Phentolamine is a potent, selective and orally active α1 adrenergic and α2 adrenergic receptor antagonist. Phentolamine can be used for the research of erectile dysfunction[1][2][3].
Web ID
– HY-12717
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C17H19N3O
Citations
– Neurosci Bull. 2023 Jun 19.|bioRxiv. 2023 Oct 13.|J Endocrinol. 2020 Mar;244(3):459-471.
References
– [1]Goldstein I I. Oral phentolamine: an alpha-1, alpha-2 adrenergic antagonist for the treatment of erectile dysfunction. Int J Impot Res. 2000 Mar;12(S1):S75-S80 |[2]Amabeoku G, et al. Strychnine-induced seizures in mice: the role of noradrenaline. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Jul;18(4):753-63.|[3]Fagerholm V, et al. alpha2A-adrenoceptor antagonism increases insulin secretion and synergistically augments the insulinotropic effect of glibenclamide in mice. Br J Pharmacol. 2008 Jul;154(6):1287-96.
CAS Number
– 50-60-2
Molecular Weight
– 281.35
SMILES
– OC1=CC=CC(N(CC2=NCCN2)C3=CC=C(C)C=C3)=C1
Clinical Information
– Launched
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
