PHA-665752
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PHA-665752

SKU T6128-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 94 CAD through 779 CAD

Products Details

Product Description

– PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.

Web ID

– T6128

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H34Cl2N4O4S

Citations

– 1. Yuan S, Gong Y, Chen R, et al. Chinese herbal formula QHF inhibits hepatocellular carcinoma metastasis via HGF/c-Met signaling pathway. Biomedicine & Pharmacotherapy. 2020, 132: 110867.

References

– Christensen JG, et al. Cancer Res, 2003, 63(21), 7345-7355.

CAS Number

– 477575-56-7

Molecular Weight

– C32H34Cl2N4O4S

Compound Purity

– 0.9935

SMILES

– C(=C1/C=2C(NC1=O)=CC=C(S(CC3=C(Cl)C=CC=C3Cl)(=O)=O)C2)C4=C(C)C(C(=O)N5[C@@H](CN6CCCC6)CCC5)=C(C)N4

Pathway

– Angiogenesis|||Autophagy|||Cytoskeletal Signaling|||Apoptosis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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