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PF-543 hydrochloride
Price range: 53 CAD through 821 CAD
Products Details
Product Description
– PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
Web ID
– T8840
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H32ClNO4S
Citations
– 1. Zhang L, Yi Y, Wang T, et al.25-Hydroxycholesterol inhibits classical swine fever virus entry into porcine alveolar macrophages by depleting plasma membrane cholesterol.Veterinary Microbiology.2023: 109668.
References
– Schnute ME, McReynolds MD, Kasten T, et al. Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1. Biochem J. 2012;444(1):79-88. doi:10.1042/BJ20111929
CAS Number
– 1706522-79-3
Molecular Weight
– C27H32ClNO4S
Compound Purity
– 0.9992
SMILES
– Cl.Cc1cc(CS(=O)(=O)c2ccccc2)cc(OCc2ccc(CN3CCC[C@@H]3CO)cc2)c1
Pathway
– GPCR/G Protein|||Apoptosis|||Autophagy
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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