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PF-4989216
Price range: 53 CAD through 952 CAD
Products Details
Product Description
– PF-4989216 is a potent and selective PI3K inhibitor with IC50 values of 2 nM (p110α), 142 nM (p110β), 65 nM (p110γ), 1 nM (p110δ), and 110 nM (VPS34).
Web ID
– T6938
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H13FN6OS
Citations
– 1. Liao W, Wang Z, Han Y, et al. Design, synthesis and biological activity of novel 2,3,4,5-tetra-substituted thiophene derivatives as PI3Kα inhibitors with potent antitumor activity. European Journal of Medicinal Chemistry. 2020, 197: 112309
References
– Walls M, et al. Clin Cancer Res. 2014, 20(3), 631-643.
CAS Number
– 1276553-09-3
Molecular Weight
– C18H13FN6OS
Compound Purity
– 0.9953
SMILES
– Fc1cc(ccc1-c1c(sc(N2CCOCC2)c1C#N)-c1ncn[nH]1)C#N
Pathway
– PI3K/Akt/mTOR signaling|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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