PF-06751979
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PF-06751979

SKU T12429-25 mg Category Brand:

Price range: 1,968 CAD through 2,576 CAD

Products Details

Product Description

– PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).

Web ID

– T12429

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H19F2N5O3S2

References

– O’Neill BT, et al. Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation. J Med Chem. 2018 May 24;61(10):4476-4504.

CAS Number

– 1818339-66-0

Molecular Weight

– C18H19F2N5O3S2

SMILES

– [H][C@]12CSC(N)=N[C@]1(CO[C@@H](C)C2)c1nc(NC(=O)c2ccc(OC(F)F)cn2)cs1

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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