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PF-06465469
$220 – $340
Products Details
Product Description
– PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM[1].
Web ID
– HY-108691
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C30H33N7O2
References
– [1]Mamand S, et al. Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma. Sci Rep. 2018 Sep 21;8(1):14216.
CAS Number
– 1407966-77-1
Molecular Weight
– 523.63
Compound Purity
– 99.48
SMILES
– O=C(NC1=CC=C(C(C)C)C(C)=C1)C2=CC=CC(C3=NN([C@H]4CN(C(C=C)=O)CCC4)C5=NC=NC(N)=C53)=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 11 mg/mL (ultrasonic)
Target
– Itk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
