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PF-06273340
SKU
HY-122616-1 mg
Category Reference compound
Tags Inflammation/Immunology, Neuronal Signaling;Protein Tyrosine Kinase/RTK, Trk Receptor
$120 – $580
Products Details
Product Description
– PF-06273340 is a potent, selective, orally bioavailable and peripherally restricted pan Trk inhibitor[1].
Web ID
– HY-122616
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H22ClN7O3
References
– [1]Skerratt SE, et al. The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain.
CAS Number
– 1402438-74-7
Molecular Weight
– 479.92
Compound Purity
– 98.0
SMILES
– O=C(NC1=CC(C(C2=CN(C(C)(C)CO)C3=NC(N)=NC=C32)=O)=CN=C1)CC4=NC=C(Cl)C=C4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Trk Receptor
Isoform
– Trk
Pathway
– Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.