PF-06250112

SKU T12673L-25 mg Category Brand:

Price range: 3,152 CAD through 5,440 CAD

Products Details

Product Description

– PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM. PF-06250112 displays an inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC (IC50s: 0.9 nM and 1.2 nM, respectively).

Web ID

– T12673L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H20F2N6O2

References

– Rankin AL, et al. Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis. J Immunol. 2013 Nov 1;191(9):4540-50.

CAS Number

– 1609465-89-5

Molecular Weight

– C22H20F2N6O2

SMILES

– C(N)(=O)C=1C(=NN(C1N)[C@@H]2CN(C#N)CCC2)C3=CC=C(OC4=C(F)C=C(F)C=C4)C=C3

Target

– Antioxidant

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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