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Products Details
Product Description
– PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM. PF-06250112 displays an inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC (IC50s: 0.9 nM and 1.2 nM, respectively).
Web ID
– T12673L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H20F2N6O2
References
– Rankin AL, et al. Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis. J Immunol. 2013 Nov 1;191(9):4540-50.
CAS Number
– 1609465-89-5
Molecular Weight
– C22H20F2N6O2
SMILES
– C(N)(=O)C=1C(=NN(C1N)[C@@H]2CN(C#N)CCC2)C3=CC=C(OC4=C(F)C=C(F)C=C4)C=C3
Target
– Antioxidant
Pathway
– Angiogenesis|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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