PF-04634817 succinate
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PF-04634817 succinate

SKU T12419-25 mg Category Brand:

Price range: 2,912 CAD through 4,960 CAD

Products Details

Product Description

– PF-0463481 succinate is a potent and orally active dual antagonist of CCR2/CCR5, exhibiting comparable human and rodent CCR2 potency with an IC50 of 20.8 nM.

Web ID

– T12419

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H42F3N5O7

References

– Tesch GH, et al. Combined inhibition of CCR2 and ACE provides added protection against progression of diabetic nephropathy in Nos3-deficient mice.Am J Physiol Renal Physiol. 2019 Dec 1;317(6):F1439-F1449.

CAS Number

– 2140301-98-8

Molecular Weight

– C29H42F3N5O7

SMILES

– C(CC(O)=O)C(O)=O.C(=O)([C@]1(C(C)C)C[C@H](N[C@@H]2[C@H](OC)COCC2)CC1)N3[C@@H]4CN([C@H](C3)C4)C=5C=C(C(F)(F)F)N=CN5

Pathway

– Immunology/Inflammation|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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