PF-00835231

SKU T9458-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 83 CAD through 1,427 CAD

Products Details

Product Description

– PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively. PF-00835231 is the active compound of the first anti-3CLpro regimen in clinical trials.

Web ID

– T9458

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H32N4O6

References

– Robert L Hoffman, et al. Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19. J Med Chem. 2020 Nov 12;63(21):12725-12747.

CAS Number

– 870153-29-0

Molecular Weight

– C24H32N4O6

Compound Purity

– 0.993

SMILES

– COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO

Pathway

– Microbiology/Virology

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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