Peimisine

SKU T5S0106-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 706 CAD

Products Details

Product Description

– 1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Peimisine can attenuate lung tissue injury( ALI), LDH and MDA amount in ALI mice in a dose dependent manner, it also lower the total protein, total white blood cells, lymphocyte and neutrophilic leukocyte in bronchoalveolar lavage fluid( BALF); suggests that peimisine can play a protective role against LPS-induced acute lung injury. 3. Peimisine has the protective effect on the experimental hepatic fibrosis formation, the possible mechanisms are associated with inhibiting fibrogenesis and fibrosis accumulation, and decreasing lipid peroxidation. 4. Peimisine can inhibit angiotensin I converting enzyme activity in a dose-dependent manner, displaying 5 % inhibitory concentration values of 526.5 microM, thus, it may have antihypertensive action.

Web ID

– T5S0106

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H41NO3

Citations

– 1. Shim K S, Gu D R, Hwang Y H, et al. Water Extract of Fritillariae thunbergii Bulbus Inhibits RANKL-Mediated Osteoclastogenesis and Ovariectomy-Induced Trabecular Bone Loss. Molecules. 2022, 27(1): 169.

References

– Liu J , Xu X F , Guo C Y , et al. Protection of peimisine on hepatic fibrosis of rats induced by CCl4[J]. Chinese Traditional & Herbal Drugs, 2013, 44(11):1455-1459.

CAS Number

– 19773-24-1

Molecular Weight

– C27H41NO3

Compound Purity

– 0.9899

SMILES

– C[C@@H]1[C@@H]2NC[C@@H](C)C[C@H]2O[C@]11CC[C@H]2[C@@H]3CC(=O)[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC2=C1C

Pathway

– Neuroscience|||Endocrinology/Hormones

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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