PDD00031705

$350$3,200

Products Details

Product Description

– PDD00031705 is a benzimidazolone core cell-inactive inhibitor of Poly (ADP-ribose) glycohydrolase (PARG)[1].

Web ID

– HY-135846

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C20H22N6O3S3

References

– [1]James DI, et al. First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to AZD2281. ACS Chem Biol. 2016 Nov 18;11(11):3179-3190. Epub 2016 Oct 12.

CAS Number

– 2032096-45-8

Molecular Weight

– 490.62

Compound Purity

– 99.20

SMILES

– O=S(C1=CC=C(N2CC3=C(C)N=C(C)S3)C(N(C4=NC=NS4)C2=O)=C1)(N(C)C5(C)CC5)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Poly(ADP-ribose) Glycohydrolase (PARG)

Pathway

– Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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