PD-1/PD-L1-IN-9
Add to CompareAdded to Compare

Download Files:

PD-1/PD-L1-IN-9

SKU T9651-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 88 CAD through 1,888 CAD

Products Details

Product Description

– PD-1/PD-L1-IN-9, with an IC50 of 3.8 nM, is a potent and orally active inhibitor of the PD-1/PD-L1 interaction. It enhances the immune cells’ ability to kill tumor cells and demonstrates significant antitumor activity in vivo in a CT26 mouse model.

Web ID

– T9651

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H24N2O2

References

– Wang T, et, al. Novel Biphenyl Pyridines as Potent Small-Molecule Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction. J Med Chem. 2021 May 30.

CAS Number

– 2628506-54-5

Molecular Weight

– C22H24N2O2

Compound Purity

– 0.9937

SMILES

– COc1nc(ccc1CNCCO)-c1cccc(c1C)-c1ccccc1

Pathway

– Immunology/Inflammation|||Apoptosis|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
6-Mercaptopurine
6-Mercaptopurine Price range: 50 CAD through 190 CAD
1 g1 mL * 10 mM (in DMSO)25 mg

1000 in stock

Select options
Mecarbinate
Mecarbinate Price range: 46 CAD through 56 CAD
1 g1 mL * 10 mM (in DMSO)

1000 in stock

Select options
Procainamide hydrochloride
Procainamide hydrochloride Price range: 50 CAD through 317 CAD
1 g1 mL * 10 mM (in DMSO)25 mg

1000 in stock

Select options
7-Chloro-4-(piperazin-1-yl)quinoline
7-Chloro-4-(piperazin-1-yl)quinoline Price range: 56 CAD through 77 CAD
100 mg200 mg

1000 in stock

Select options
4-Methoxycoumarine
4-Methoxycoumarine Price range: 56 CAD through 266 CAD
1 g1 mL * 10 mM (in DMSO)50 mg

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });