Products Details

Product Description

– PCSK9-IN-2 is a newly developed small molecule that effectively inhibits the protein-protein interaction (PPI) between PCSK9 and LDLR. It has been found to have a potent inhibitory activity with an IC50 value of 7.57 μM.

Web ID

– T39528

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H32N6O6

References

– Sun H, et al. Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction. J Chem Inf Model. 2021 Oct 25;61(10):5269-5279.

CAS Number

– 2099167-44-7

Molecular Weight

– C26H32N6O6

SMILES

– O=C1C[C@@H](N[C@@H]2CCCCNC2=O)C(=O)N1c1ccc(cc1)N1C(=O)C[C@@H](N[C@@H]2CCCCNC2=O)C1=O

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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