PCO371

$300$2,200

$480
Only 1000 item(s) left in stock.

Products Details

Product Description

– PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.

Web ID

– HY-100856

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C29H32F3N5O6S

References

– [1]Tamura T, et al. Identification of an orally active small-molecule PTHR1 agonist for the treatment of hypoparathyroidism. Nat Commun. 2016 Nov 18;7:13384.

CAS Number

– 1613373-33-3

Molecular Weight

– 635.65

Compound Purity

– 98.82

SMILES

– FC(F)(F)OC1=CC=C(C2=NC3(CCN(S(CCC4=C(C)C=C(N5C(NC(C5(C)C)=O)=O)C=C4C)(=O)=O)CC3)C(N2)=O)C=C1

Clinical Information

– Phase 1

Research Area

– Endocrinology

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Thyroid Hormone Receptor

Pathway

– Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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