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Products Details
Product Description
– PBI-6DNJ is an orally active and potent multivalent glycosidase inhibitor. PBI-6DNJ exhibits good inhibition activity against α-glucosidase from mice, with a Ki of 0.14 μM. PBI-6DNJ exhibits good hypoglycemic activity. PBI-6DNJ can be used for type 2 diabetes research[1].
Web ID
– HY-150723
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C120H146N26O36
References
– [1]Jian-XingYang, et al. Multivalent glucosidase inhibitors based on perylene bisimide and iminosugar conjugates. European Journal of Medicinal Chemistry. 2022 November 5, 241(3):114621.
Molecular Weight
– 2528.60
SMILES
– OC[C@H]1[C@@H]([C@H]([C@@H](CN1CCCN2C=C(COC3=CC=C(C=C3)OC4=CC(C(N5CC6=CN(CCCN7[C@@H](CO)[C@@H]([C@H]([C@@H](C7)O)O)O)N=N6)=O)=C8C9=C4C%10=C%11C(C(C%12=O)=CC(OC%13=CC=C(C=C%13)OCC%14=CN(CCCN%15[C@H](CO)[C@H]([C@@H]([C@H](C%15)O)O)O)N=N%14)=C%11C9=C(C=C8C5=O)OC%16=CC=C(C=C%16)OCC%17=CN(CCCN(C[C@H]([C@@H]([C@H]%18O)O)O)[C@H]%18CO)N=N%17)=C(C=C%10OC%19=CC=C(OCC%20=CN(CCCN%21[C@H](CO)[C@H]([C@@H]([C@H](C%21)O)O)O)N=N%20)C=C%19)C(N%12CC%22=CN(CCCN%23[C@H](CO)[C@H]([C@@H]([C@H](C%23)O)O)O)N=N%22)=O)N=N2)O)O)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Glucosidase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
