Parthenolide
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Parthenolide

SKU T2140-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 80 CAD through 190 CAD

Products Details

Product Description

– Parthenolide ((-)-Parthenolide) is a natural sesquiterpene lactone that is an NF-κB inhibitor and also specifically inhibits HDAC1 protein, but is inactive against other class I/II HDACs. Parthenolide has anti-inflammatory, anti-tumor, and anti-viral activities.

Web ID

– T2140

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H20O3

Citations

– 1. Fu Z, Duan Y, Pei H, et al.Discovery of Potent, Specific, and Orally Available NLRP3 Inflammasome Inhibitors Based on Pyridazine Scaffolds for the Treatment of Septic Shock and Peritonitis.Journal of Medicinal Chemistry.2024

References

– Nakshatri, H., Appaiah, H., Anjanappa, M., Gilley, D., Tanaka, H., & Badve, S. et al. (2015). NF-κB-dependent and -independent epigenetic modulation using the novel anti-cancer agent DMAPT. Cell Death & Disease, 6(1), e1608-e1608. doi: 10.1038/cddis.2014.569

CAS Number

– 20554-84-1

Molecular Weight

– C15H20O3

Compound Purity

– 0.9933

SMILES

– CC1=C/CC[C@@]2(C)O[C@H]2[C@H]2OC(=O)C(=C)[C@@H]2CC1

Pathway

– DNA Damage/DNA Repair|||NF-κB|||Apoptosis|||Autophagy|||Chromatin/Epigenetic

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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