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Products Details
Product Description
– PARP7-IN-15 (Compound 18) is a PARP7 inhibitor with IC50 of 0.56 nM, that has antitumor activity[1].
Web ID
– HY-155351
Shipping
– Room temperature
Molecular Formula
– C23H24F6N6O4
References
– [1]Silong Zhang , et al. Exploring the structural-activity relationship of hexahydropyrazino[1,2-d]pyrido[3,2-b][1,4]oxazine derivatives as potent and orally-bioavailable PARP7 inhibitors. Eur J Med Chem. 2023 Oct 8:261:115836.
CAS Number
– 2819998-97-3
Molecular Weight
– 562.46
SMILES
– O=C1C(C(F)(F)F)=C(N2CC[C@H]2COCCC(N3C[C@@H](COC4=C5N=CC(C(F)(F)F)=C4)N5CC3)=O)C=NN1
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– PARP
Isoform
– PARP7
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
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