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Paricalcitol-d6
$600 – $4,800
Products Details
Product Description
– Paricalcitol-d6 is the deuterium labeled Paricalcitol. Paricalcitol is a agent used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure[1].
Web ID
– HY-76585
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C27H38D6O3
References
– [1]Martinez-Moreno JM, et al.
In vascular smooth muscle cells paricalcitol prevents phosphate-induced Wnt/beta-catenin activation.
Am J Physiol Renal Physiol. 2012 Aug 8.|[2]Ari E, Kedrah AE, Alahdab Y, Bulut G, Eren Z, Baytekin O, Odabasi D.
Antioxidant and renoprotective effects of paricalcitol on experimental contrast-induced nephropathy model.
Br J Radiol. 2012 Aug;85(1016):1038-43.|[3]Meems LM, Cannon MV, Mahmud H, Voors AA, van Gilst WH, Silljé HH, Ruifrok WP, de Boer RA.
The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload.
J Steroid Biochem Mol Biol. 2012 Jul 16;132(3-5):282-289.|[4]Blanco-GarcÃa R, et al.
Microalbuminuria, another use for paricalcitol? Our experience in advanced chronic kidney disease.
Nefrologia. 2012 May 14;32(3):401-2. doi: 10.3265/Nefrologia.pre2012.Feb.11378.|[5]Piao SG, Song JC, Lim SW, Chung BH, Choi BS, Yang CW.
Protective effect of paricalcitol on cyclosporine-induced renal injury in rats.
Transplant Proc. 2012 Apr;44(3):642-5.
CAS Number
– 2070009-67-3
Molecular Weight
– 422.67
Compound Purity
– 99.64
SMILES
– C[C@]([C@@H]([C@@H](/C=C/[C@@H](C(C([2H])([2H])[2H])(C([2H])([2H])[2H])O)C)C)CC1)(CCC/2)[C@@]1(C2=CC=C3C[C@H](C[C@@H](C/3)O)O)[H]
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– VD/VDR
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
