Pan-RAF kinase inhibitor 1

SKU HY-142452-Get quote Category Tags , ,

Products Details

Product Description

– Pan-RAF kinase inhibitor 1 is a potent inhibitor of Pan-RAF kinase. Pan-RAF kinase inhibitor 1 regulates MAPK signaling by inhibiting RAF kinase, thereby exerting an effect on the proliferation of RAS-mutant tumor cells. Pan-RAF kinase inhibitor 1 has the potential for the research of cancer diseases (extracted from patent WO2021110141A1, compound 16B)[1].

Web ID

– HY-142452

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C26H24F3N3O4

References

– [1]Zhaozhong Ding, et al. Biaryl Compounds of Pan-RAF Kinase Inhibitors. Patent WO2021110141A1.

CAS Number

– 2648838-76-8

Molecular Weight

– 499.48

SMILES

– OCCOC1=NC([C@]23[C@](COC3)([H])C2)=CC(C4=CC(NC(C5=CC=NC(C(F)(F)F)=C5)=O)=CC=C4C)=C1

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Raf

Pathway

– MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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