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Products Details
Product Description
– Pan-RAF kinase inhibitor 1 is a potent inhibitor of Pan-RAF kinase. Pan-RAF kinase inhibitor 1 regulates MAPK signaling by inhibiting RAF kinase, thereby exerting an effect on the proliferation of RAS-mutant tumor cells. Pan-RAF kinase inhibitor 1 has the potential for the research of cancer diseases (extracted from patent WO2021110141A1, compound 16B)[1].
Web ID
– HY-142452
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H24F3N3O4
References
– [1]Zhaozhong Ding, et al. Biaryl Compounds of Pan-RAF Kinase Inhibitors. Patent WO2021110141A1.
CAS Number
– 2648838-76-8
Molecular Weight
– 499.48
SMILES
– OCCOC1=NC([C@]23[C@](COC3)([H])C2)=CC(C4=CC(NC(C5=CC=NC(C(F)(F)F)=C5)=O)=CC=C4C)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Raf
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
