PA452

$105$2,450

Products Details

Product Description

– PA452, retinoic X receptor (RXR) specific antagonist, inhibits the effect of Retinoic acid (RA) on Th1/Th2 development[1].

Web ID

– HY-108522

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C26H37N3O3

References

– [1]Iwata M, et al. Retinoic acids exert direct effects on T cells to suppress Th1 development and enhance Th2 development via retinoic acid receptors. Int Immunol. 2003 Aug;15(8):1017-25.|[2]Varley CL, et al. Activation of peroxisome proliferator-activated receptor-gamma reverses squamous metaplasia and induces transitional differentiation in normal human urothelial cells. Am J Pathol. 2004 May;164(5):1789-98.

CAS Number

– 457657-34-0

Molecular Weight

– 439.59

Compound Purity

– 99.0

SMILES

– O=C(C1=CN=C(N(C2=C(OCCCCCC)C=C3C(C)(C)CCC(C)(C)C3=C2)C)N=C1)O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– DMSO : 40 mg/mL (ultrasonic;warming)|Ethanol : 4.4 mg/mL (ultrasonic;warming)

Target

– RAR/RXR

Pathway

– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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