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p38-α MAPK-IN-1
$130 – $2,250
Products Details
Product Description
– p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay[1].
Web ID
– HY-18874
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C27H35N5O3
References
– [1]Kluter S, et al. Displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem. 2010 Jan 14;53(1):357-67.
CAS Number
– 443913-15-3
Molecular Weight
– 477.60
Compound Purity
– 99.89
SMILES
– CC1=CC=C(N2C(NC(NC3=CC=C(OCCN4CCOCC4)C=C3)=O)=CC(C(C)(C)C)=N2)C=C1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Autophagy;p38 MAPK
Pathway
– Autophagy;MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
