Download Files:
Products Details
Product Description
– P2X3 antagonist 38 (compound 4) is a potent and orally active P2X3 antagonist with IC50 values of 0.132, 0.165, 0.421 µM for hP2X3, rP2X3, gpP2X3, respectively[1].
Web ID
– HY-153710
Shipping
– Room temperature
Molecular Formula
– C22H25F3N6O3
References
– [1]YunFeng Chen, et al. N-carboxamidopyrazoline derivative serving as p2x3 receptor antagonist and applications. WO2022028154A1.
CAS Number
– 2545974-71-6
Molecular Weight
– 478.47
SMILES
– CCOC(N([C@@H]1C(C2=CC=C(C=C2)C)=NN(C1)C(N[C@@H](C3=CN=C(C(F)(F)F)N=C3)C)=O)C)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– P2X Receptor
Isoform
– P2X3 Receptor
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
