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Products Details
Product Description
– P2X3 antagonist 38 (compound 4) is a potent and orally active P2X3 antagonist with IC50 values of 0.132, 0.165, 0.421 µM for hP2X3, rP2X3, gpP2X3, respectively[1].
Web ID
– HY-153710
Shipping
– Room temperature
Molecular Formula
– C22H25F3N6O3
References
– [1]YunFeng Chen, et al. N-carboxamidopyrazoline derivative serving as p2x3 receptor antagonist and applications. WO2022028154A1.
CAS Number
– 2545974-71-6
Molecular Weight
– 478.47
SMILES
– CCOC(N([C@@H]1C(C2=CC=C(C=C2)C)=NN(C1)C(N[C@@H](C3=CN=C(C(F)(F)F)N=C3)C)=O)C)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– P2X Receptor
Isoform
– P2X3 Receptor
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
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