Osunprotafib

SKU T61699-1 mg Category Brand:

Price range: 728 CAD through 7,888 CAD

Products Details

Product Description

– Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors. [1] Osunprotafib (ABBV-CLS-484) stimulates the tumor microenvironment and promotes natural killer cell and CD8 T cell function and enhances T cell anti-tumor immunity by enhancing JAK-STAT signaling and reducing T cell dysfunction. [2]

Web ID

– T61699

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H24FN3O4S

References

– Philip R, et al. Protein tyrosine phosphatase inhibitors and methods of use thereof. WO2022056281A1.

CAS Number

– 2489404-97-7

Molecular Weight

– C17H24FN3O4S

Compound Purity

– 0.9824

SMILES

– CC(C)CCN[C@@H]1CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2C1

Pathway

– Metabolism

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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