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Products Details
Product Description
– Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors. [1] Osunprotafib (ABBV-CLS-484) stimulates the tumor microenvironment and promotes natural killer cell and CD8 T cell function and enhances T cell anti-tumor immunity by enhancing JAK-STAT signaling and reducing T cell dysfunction. [2]
Web ID
– T61699
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C17H24FN3O4S
References
– Philip R, et al. Protein tyrosine phosphatase inhibitors and methods of use thereof. WO2022056281A1.
CAS Number
– 2489404-97-7
Molecular Weight
– C17H24FN3O4S
Compound Purity
– 0.9824
SMILES
– CC(C)CCN[C@@H]1CCc2cc(O)c(N3CC(=O)NS3(=O)=O)c(F)c2C1
Pathway
– Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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