Osimertinib dimesylate

SKU T10433-2 mg Category Brand:

Price range: 48 CAD through 88 CAD

Products Details

Product Description

– Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).

Web ID

– T10433

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H41N7O8S2

References

– Cross DA, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov. 2014 Sep;4(9):1046-61.

CAS Number

– 2070014-82-1

Molecular Weight

– C30H41N7O8S2

SMILES

– CS(O)(=O)=O.CS(O)(=O)=O.COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12

Target

– Others

Pathway

– Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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