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Oleandrin
Price range: 157 CAD through 4,624 CAD
Products Details
Product Description
– 1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, K-ATPase pump, resulting in a consequent increase in calcium influx in heart muscle. 3. Oleandrin has stronger anti-proliferative activity in undifferentiated CaCO-2 cells (IC50, 8.25 nM) , causes an autophagic cell death and altered ERK phosphorylation in undifferentiated.
Web ID
– T5S0890
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C32H48O9
Citations
– 1. Pan L, Zhang Y, Zhao W, et al. The cardiac glycoside oleandrin induces apoptosis in human colon cancer cells via the mitochondrial pathway. Cancer Chemotherapy and Pharmacology. 2017 Jul;80(1):91-100
References
– Raviprakash N , Manna S K . Short-term exposure to oleandrin enhances responses to IL-8 by increasing cell surface IL-8 receptors[J]. British Journal of Pharmacology, 2014, 171(14):3339-3351.
CAS Number
– 465-16-7
Molecular Weight
– C32H48O9
Compound Purity
– 0.9973
SMILES
– [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@H]([C@H](C[C@]34O)OC(C)=O)C3=CC(=O)OC3)[C@@]1(C)CC[C@@H](C2)O[C@H]1C[C@H](OC)[C@@H](O)[C@H](C)O1
Pathway
– Apoptosis|||Membrane transporter/Ion channel
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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