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Olacaftor
SKU
HY-112267-10 mg
Category Reference compound
Tags Autophagy;CFTR, Autophagy;Membrane Transporter/Ion Channel, Inflammation/Immunology
$900 – $7,450
Products Details
Product Description
– Olacaftor (VX-440) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator extracted from patent US9782408.
Web ID
– HY-112267
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C29H34FN3O4S
References
– [1]Miller M, et al. Modulators of cystic fibrosis transmembrane conductance regulator. US9782408.
CAS Number
– 1897384-89-2
Molecular Weight
– 539.66
Compound Purity
– 99.26
SMILES
– O=C(C1=CC=C(C2=CC(OCC(C)C)=CC(F)=C2)N=C1N3C(C)(C)C[C@H](C)C3)NS(=O)(C4=CC=CC=C4)=O
Clinical Information
– Phase 2
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Autophagy;CFTR
Pathway
– Autophagy;Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.