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OICR-9429-N-C2-NH2
SKU
HY-141798-Get quote
Category Reference compound
Tags Cancer, Ligands for Target Protein for PROTAC, PROTAC
Products Details
Product Description
– OICR-9429-N-C2-NH2 is a ligand for Wd40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1, intermediate 2. OICR-9429-N-C2-NH2 can be used in the synthesis of PROTACs[1].
Web ID
– HY-141798
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C31H38F3N7O2
References
– [1]Jin J, et, al. Wd40 repeat domain protein 5 (wdr5) degradation / disruption compounds and methods of use. WO2019246570A1.|[2]Chung CW, et, al. Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chem Biol. 2020 Sep 18;15(9):2316-2323.
CAS Number
– 2407457-55-8
Molecular Weight
– 597.67
SMILES
– CN(CC1)CCN1C(C(NC(C2=CNC(C=C2C(F)(F)F)=O)=O)=C3)=CC=C3C4=CC(CN5CCN(CCN)CC5)=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for Target Protein for PROTAC
Pathway
– PROTAC
Product type
– Reference compound
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