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Nutlin carboxylic acid
$350 – $2,500
Products Details
Product Description
– Nutlin carboxylic acid (MDM2 ligand 1) is the Nutlin 3-based MDM2 ligand. Nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTAC[1].
Web ID
– HY-128837
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C32H32Cl2N4O6
References
– [1]Hu Chunqi, et al. Dimer amide micromolecule PROTACs for inducing MDM2 to self-degrade E3 ubiquitin ligase. Patent CN108610333A.
CAS Number
– 2249750-27-2
Molecular Weight
– 639.53
Compound Purity
– 98.36
SMILES
– O=C(N1C(C2=C(C=C(C=C2)OC)OC(C)C)=N[C@@H](C3=CC=C(C=C3)Cl)[C@H]1C4=CC=C(C=C4)Cl)N5CC(N(CC(O)=O)CC5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming)
Target
– Ligands for E3 Ligase
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
