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NSC232003
SKU
HY-103236-1 mg
Category Reference compound
Tags Cancer, E1/E2/E3 Enzyme, Metabolic Enzyme/Protease
$150 – $3,350
Products Details
Product Description
– NSC232003 is a highly potent and cell-permeable UHRF1 inhibitor, which inhibits DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level.
Web ID
– HY-103236
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C6H7N3O3
References
– [1]Myrianthopoulos V, et al. Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation. Eur J Med Chem. 2016 May 23;114:390-6.
CAS Number
– 1905453-18-0
Molecular Weight
– 169.14
Compound Purity
– 99.67
SMILES
– O=C1NC(/C(C=N1)=C(NO)/C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : < 1 mg/mL|H2O : 2 mg/mL (ultrasonic)
Target
– E1/E2/E3 Enzyme
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.