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NSC 694621
$100 – $950
Products Details
Product Description
– NSC 694621 is a potent PCAF inhibitor, with an IC50 of 5.71 µM (PCAF/H31-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells[1].
Web ID
– HY-147288
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H10N2O2S
References
– [1]Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89.
CAS Number
– 104857-29-6
Molecular Weight
– 258.30
Compound Purity
– 99.01
SMILES
– O=C1C2=CC=CN=C2SN1C3=CC=C(C=C3)OC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 3.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Histone Acetyltransferase
Isoform
– GCN5/PCAF
Pathway
– Epigenetics
Product type
– Reference compound
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