NSC 66811
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NSC 66811

SKU T21578-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 477 CAD

Products Details

Product Description

– NSC 66811is a novel inhibitor of the murine double minute 2 (MDM2)-p53 interaction. It binds to MDM2 with a Ki of 120 nM and activates p53 in cancer cells with a mechanism of action consistent with targeting the MDM2-p53 interaction.

Web ID

– T21578

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H20N2O

References

– Yipin Lu, et al. Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy. J Med Chem. 2006 Jun 29;49(13):3759-62.

CAS Number

– 6964-62-1

Molecular Weight

– C23H20N2O

Compound Purity

– 0.9694

SMILES

– Cc1ccc2ccc(C(Nc3ccccc3)c3ccccc3)c(O)c2n1

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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