NSC 107512

$1,250$1,950

Products Details

Product Description

– NSC 107512 is a potent inhibitor of cyclin-dependent kinase 9 (CDK9). NSC 107512 is a class of sangivamycin-like molecules (SLM). NSC 107512 inhibits growth and induces apoptosis of multiple myeloma tumors[1].

Web ID

– HY-141687

Storage Temperature

– -20°C (Powder, protect from light, stored under nitrogen)

Shipping

– Blue Ice

Applications

– Cancer-Kinase/protease

Molecular Formula

– C12H16N6O5

References

– [1]Dolloff NG, et al. Sangivamycin-like molecule 6 exhibits potent anti-multiple myeloma activity through inhibition of cyclin-dependent kinase-9. Mol Cancer Ther. 2012;11(11):2321-2330.

CAS Number

– 22242-89-3

Molecular Weight

– 324.29

Compound Purity

– 99.41

SMILES

– O[C@H]1[C@](O[C@@H]([C@H]1O)CO)([H])N2C3=NC=NC(N)=C3C(C(NO)=N)=C2

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 170 mg/mL (ultrasonic)

Target

– Apoptosis;CDK

Pathway

– Apoptosis;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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