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Products Details
Product Description
– NMS-P945 is an ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs). NMS-P945 is suitable for conjugation to mAbs with reproducible Drug Antibody Ratio (DAR) >3.5[1].
Web ID
– HY-156299
Shipping
– Room temperature
Molecular Formula
– C61H76ClN11O12S
References
– [1]Valsasina B, Novel thienoduocarmycin-trastuzumab ADC demonstrates Strong Anti-tumor Efficacy with Favorable Safety Profile in Preclinical Studies. Mol Cancer Ther. 2023 Sep 19.
CAS Number
– 1466546-35-9
Molecular Weight
– 1222.84
SMILES
– O=C(N1CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(N(C)CCN(C)C(OC(C3=C4C(C)=CS3)=CC5=C4[C@H](CCl)CN5C(C6=CC(C=C(C=C7)OCCN8CCCC8)=C7N6)=O)=O)=O)C=C2)=O)=O)=O)C=CC1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
