Download Files:
Products Details
Product Description
– NMS-P528 is a Duocarmycin derivative that can be used as an ADC payload. NMS-P528 can be used to synthesize NMS-P945[1].
Web ID
– HY-156249
Shipping
– Room temperature
Molecular Formula
– C27H28ClN3O3S
References
– [1]Barbara Valsasina, et al. Novel thienoduocarmycin-trastuzumab ADC demonstrates Strong Anti-tumor Efficacy with Favorable Safety Profile in Preclinical Studies. Mol Cancer Ther. 2023 Sep 19.
CAS Number
– 1466546-45-1
Molecular Weight
– 510.05
SMILES
– ClC[C@@H](C1=C2C=C(O)C3=C1C(C)=CS3)CN2C(C(N4)=CC5=C4C=CC(OCCN6CCCC6)=C5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
