NLRP3-IN-70
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NLRP3-IN-70

SKU T205527-10 mg Category Brand:

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Products Details

Product Description

– NLRP3-IN-70 (Compound 5m) is an inhibitor of the NLRP3 inflammasome with low oral bioavailability. It binds directly to the NACHT domain of the NLRP3 protein, thereby blocking its interaction with ASC, which inhibits ASC oligomerization and the assembly of the NLRP3 inflammasome. NLRP3-IN-70 is applicable in studies on sepsis and non-alcoholic steatohepatitis.

Web ID

– T205527

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H23NO5

CAS Number

– 1997362-01-2

Molecular Weight

– C23H23NO5

SMILES

– O=C1C(=O)C2=C(C=CC3=C2CCCC3(C)C)C=4OC=C(C(=O)N5CCOCC5)C14

Pathway

– Immunology/Inflammation

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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