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Products Details
Product Description
– NLRP3-IN-7 (Compound 36) is a selective NLRP3 inflammasome inhibitor. NLRP3-IN-7 effectively blocks the assembly of the NLRP3 inflammasome[1].
Web ID
– HY-145911
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H15ClN2O4S3
References
– [1]Zuo D, et al. Design and synthesis of an N-benzyl 5-(4-sulfamoylbenzylidene-2-thioxothiazolidin-4-one scaffold as a novel NLRP3 inflammasome inhibitor. Bioorg Med Chem Lett. 2022 Jun 1;65:128693.
Molecular Weight
– 454.97
SMILES
– ClC1=CC=C(OC)C=C1CN2C(/C(SC2=S)=C/C3=CC=C(C=C3)S(N)(=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– NOD-like Receptor (NLR)
Isoform
– NLRP3
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
