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NLRP3/AIM2-IN-1
SKU
HY-144220-Get quote
Category Reference compound
Tags Immunology/Inflammation, Inflammation/Immunology, NOD-like Receptor (NLR)
Products Details
Product Description
– NLRP3/AIM2-IN-1 is a thermal sepsis inhibitor with an IC 50 value of 3.136 ± 0.7667 μ M.
Web ID
– HY-144220
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H16BNO4
References
– [1]Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.
Molecular Weight
– 285.10
SMILES
– COC1=CC=C(C=C1)CC(NC2=CC=CC(B(O)O)=C2)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NOD-like Receptor (NLR)
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.