Products Details

Product Description

– NLRP3/AIM2-IN-1 is a thermal sepsis inhibitor with an IC 50 value of 3.136 ± 0.7667 μ M.

Web ID

– HY-144220

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C15H16BNO4

References

– [1]Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.

Molecular Weight

– 285.10

SMILES

– COC1=CC=C(C=C1)CC(NC2=CC=CC(B(O)O)=C2)=O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– NOD-like Receptor (NLR)

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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