Download Files:
NJH-2-057
$260 – $2,100
Products Details
Product Description
– NJH-2-057 is an EN523 OTUB1 recruiter linked to lumacaftor, a agent used to treat cystic fibrosis that binds ΔF508-CFTR.
Web ID
– HY-115878
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C43H44F2N6O8
References
– [1]Henning NJ, et al. Deubiquitinase-Targeting Chimeras for Targeted Protein Stabilization. 2021 May 03.
CAS Number
– 2858812-70-9
Molecular Weight
– 810.84
Compound Purity
– 98.87
SMILES
– O=C(N1CC(N(CC1)C2=CC=C(CCC(NCCCCCNC(C3=CC=CC(C4=NC(NC(C5(CC5)C6=CC=C7OC(F)(OC7=C6)F)=O)=CC=C4C)=C3)=O)=O)O2)=O)C=C
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– CFTR
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
