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Nizatidine
$50 – $96
Products Details
Product Description
– Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models[1].
Web ID
– HY-B0310
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H21N5O2S2
References
– [1]Ahmed S. Alazzouni, et al. Comparative histological and histochemical studies between ranitidine and nizatidine in treatment of peptic ulcer with evaluation of their adverse effects on male sex hormones. The Journal of Basic and Applied Zoology volume|[2]T M Lin, et al. Actions of nizatidine, a selective histamine H2-receptor antagonist, on gastric acid secretion in dogs, rats and frogs. J Pharmacol Exp Ther. 1986 Nov;239(2):406-10.|[3]Shen Li, et al. Abstract 4004: The H2 receptor antagonist nizatidine inhibits carcinogenesis in two rodent models of hepatocellular carcinoma. Tumor Biology. Cancer research.
CAS Number
– 76963-41-2
Molecular Weight
– 331.46
Compound Purity
– 99.68
SMILES
– CN/C(NCCSCC1=CSC(CN(C)C)=N1)=C[N+]([O-])=O
Clinical Information
– Launched
Research Area
– Cancer; Endocrinology; Inflammation/Immunology
Solubility
– DMSO : ≥ 50 mg/mL|H2O : 20 mg/mL (ultrasonic)
Target
– Histamine Receptor
Isoform
– H2 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
