Nitroaspirin
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Nitroaspirin

SKU T16328-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 142 CAD through 1,525 CAD

Products Details

Product Description

– Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin that inhibits cyclooxygenase. It induces cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells by down-regulating EGFR/PI3K/STAT3 signaling and modulating Bcl-2 family proteins. Additionally, Nitroaspirin possesses antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1.

Web ID

– T16328

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H13NO7

References

– Bertuglia S, et al. Antioxidant activity of nitro derivative of aspirin against ischemia-reperfusion in hamster cheekpouch microcirculation. Am J Physiol Gastrointest Liver Physiol. 2004 Mar;286(3):G437-43.

CAS Number

– 175033-36-0

Molecular Weight

– C16H13NO7

Compound Purity

– 0.9845

SMILES

– O(C(C)=O)C1=C(C(OC2=CC(CON(=O)=O)=CC=C2)=O)C=CC=C1

Target

– Others

Pathway

– Apoptosis|||Immunology/Inflammation|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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