NITD-916

SKU T60774-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 525 CAD through 2,544 CAD

Products Details

Product Description

– NITD-916 is an orally active and highly lipophilic inhibitor of Mycobacterium enoyl reductase InhA with an IC50 of 570 nM.NITD-916 is a potent 4-hydroxy-2-pyridone derivative that forms a ternary complex with InhA and NADH, preventing access to the fatty acyl substrate-binding pocket.NITD-916 exhibits antituberculosis activity.

Web ID

– T60774

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H25NO2

References

– Manjunatha UH, et al. Direct inhibitors of InhA are active against Mycobacterium tuberculosis. Sci Transl Med. 2015 Jan 7;7(269):269ra3.

CAS Number

– 1614262-83-7

Molecular Weight

– C20H25NO2

Compound Purity

– 0.9978

SMILES

– OC1=C(C2=CC=CC=C2)C(=O)NC(CC3CCC(C)(C)CC3)=C1

Pathway

– Microbiology/Virology

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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